Envía por correo este artículo 
Epidemiología global de las infecciones del tracto urinario por Escherichia Coli
Resumen
Las infecciones del tracto urinario (ITU) se consideran una de las patologias bacterianas más comunes, y Escherichia coli es el principal patógeno responsable. Estas infecciones afectan significativamente la calidad de vida y representan un desafío importante para la salud pública a nivel mundial. El objetivo de este estudio fue analizar la epidemiología global de las ITU causadas por Escherichia coli, evaluando la prevalencia en diferentes contextos geográficos y demográficos, con el fin de identificar patrones y factores que influencian estas infecciones. Este trabajo se basó en una revisión de artículos publicados entre 2020 y 2024 que reportan datos sobre la prevalencia de ITU por E. coli. Los estudios seleccionados incluyeron diferentes tipos de diseño, como estudios transversales y retrospectivos, y abarcaron diversas poblaciones, incluyendo mujeres gestantes, niños y adultos diabéticos, entre otros. Los resultados de la revisión mostraron una considerable variabilidad en la prevalencia de ITU por E. coli. Los porcentajes más altos de infección por E. Coli se observaron en mujeres gestantes de Ecuador (91%) y en poblaciones mixtas de Perú (85%). En contraste, los porcentajes más bajos se reportan en adultos diabéticos de Arabia Saudita (17%) y en mujeres gestantes de Somalia (19%), estas diferencias resaltaron la influencia de factores geográficos y demográficos en la epidemiología de las ITU por E. coli. En conclusión la epidemiología de las ITU por Escherichia coli es compleja y muestra una significativa variabilidad según el contexto geográfico y demográfico.
Palabras clave
Referencias
Kaur R, Kaur R. Symptoms, risk factors, diagnosis and treatment of urinary tract infections. Postgrad Med J [Internet]. 2021 Dec 1;97(1154):803–12. Available from: https://doi.org/10.1136/postgradmedj-2020-139090
Medina M, Castillo-Pino E. An introduction to the epidemiology and burden of urinary tract infections. Ther Adv Urol [Internet]. 2019;11(4):1756. Available from: https://doi.org/10.1177%2F1756287219832172
Zhou Y, Zhou Z, Zheng L, Gong Z, Li Y, Jin Y, et al. Urinary Tract Infections Caused by Uropathogenic Escherichia coli: Mechanisms of Infection and Treatment Options. Int J Mol Sci. 2023 Jun;24(13):10537.
Whelan S, Lucey B, Finn K. Uropathogenic Escherichia coli (UPEC)-Associated Urinary Tract Infections: The Molecular Basis for Challenges to Effective Treatment [Internet]. Vol. 11, Microorganisms. 2023. p. 12–20. Available from: https://doi.org/10.3390/microorganisms11092169
R. MA, Min GH, Alice G, J. ET, D. FC, D. PJD. Global Extraintestinal Pathogenic Escherichia coli (ExPEC) Lineages. Clin Microbiol Rev [Internet]. 2019 Jun 12;32(3):10.1128/cmr.00135-18. Available from: https://doi.org/10.1128/cmr.00135-18
Eberly AR, Floyd KA, Beebout CJ, Colling SJ, Fitzgerald MJ, Stratton CW, et al. Biofilm Formation by Uropathogenic Escherichia coli Is Favored under Oxygen Conditions That Mimic the Bladder Environment [Internet]. Vol. 18, International Journal of Molecular Sciences. 2017. Available from: https://doi.org/10.3390/ijms18102077
Schüroff PA, Abe CM, Silva JW, de Paula Coelho C, Andrade FB, Hernandes RT, et al. Role of aggregate-forming pilus (AFP) in adherence and colonization of both intestinal and urinary tracts. Virulence [Internet]. 2022 Dec 31;13(1):1423–33. Available from: https://doi.org/10.1080/21505594.2022.2112818
Chu C, Lowder J. Diagnosis and treatment of urinary tract infections across age groups. Am J Obstet Gynecol [Internet]. 2018 Jul 1;219(1):40–51. Available from: https://doi.org/10.1016/j.ajog.2017.12.231
Barnawi Y, Alghamdi A, Ibrahim A, Al-Anazi L, Alhumaida G, Alotaibi R, et al. Prevalence of urinary tract infections in pregnant women and antimicrobial resistance patterns in women in Riyadh, Saudi Arabia: a retrospective study. BMC Infect Dis [Internet]. 2024;24(1):502. Available from: https://doi.org/10.1186/s12879-024-09385-y
Macas Vélez J, Ortiz Tejedor JG. Caracterización de infección del tracto urinario a partir de urocultivos positivos aislados de mujeres embarazadas de la ciudad de Machala año 2022. Anatomía Digit [Internet]. 2024 Mar 5 [cited 2024 Jul 5];7(1):69–84. Available from: https://cienciadigital.org/revistacienciadigital2/index.php/AnatomiaDigital/article/view/2952
He XT, Chang CN, Yu CH, Wang CC. The risk factors, antimicrobial resistance patterns, and outcomes associated with extended-spectrum β-lactamases-Producing pathogens in pediatric urinary tract infection. Pediatr Neonatol [Internet]. 2024;65(3):242–8. Available from: https://www.sciencedirect.com/science/article/pii/S1875957223001869
PRASAD RAO M, SREEDEVI K, SRIKANTH A, DIVYA DHARSHINI B. Prevalence of urinary tract infections among females of reproductive age group in tertiary care teaching hospital. Asian J Pharm Clin Res [Internet]. 2023 Sep 7 [cited 2024 Jul 5];16(5):163–6. Available from: https://journals.innovareacademics.in/index.php/ajpcr/article/view/47816
Gebretensaie Y, Atnafu A, Girma S, Alemu Y, Desta K. Prevalence of Bacterial Urinary Tract Infection, Associated Risk Factors, and Antimicrobial Resistance Pattern in Addis Ababa, Ethiopia: A Cross-Sectional Study. Infect Drug Resist [Internet]. 2023 May 16 [cited 2024 Jul 5];16:3041–50. Available from: https://www.dovepress.com/prevalence-of-bacterial-urinary-tract-infection-associated-risk-factor-peer-reviewed-fulltext-article-IDR
Shirvani M, Keramati A, Esmaeli M. Evaluating the pattern of antibiotic resistance of urinary tract infection (UTI)-causing bacteria in the urine culture samples of patients in the infectious ward of Imam Khomeini Hospital, Kermanshah, in Iran from 2016–2018. African J Urol [Internet]. 2023;29(1):32. Available from: https://doi.org/10.1186/s12301-023-00364-4
Mera-Lojano LD, Mejía-Contreras LA, Cajas-Velásquez SM, Guarderas-Muñoz SJ. Prevalencia y factores de riesgo de infección del tracto urinario en embarazadas. Rev Med Inst Mex Seguro Soc [Internet]. 2023 [cited 2024 Jul 5];61(5):590. Available from: https://www.imbiomed.com.mx/articulo.php?id=117990
Mohamed FY, Dahie HA, Mohamoud JH, Adam MH, Dirie HM. Prevalence, antimicrobial susceptibility profile, and associated risk factors of uropathogenic Escherichia coli among pregnant women attending Dr. Sumait Hospital Mogadishu, Somalia. Front public Heal [Internet]. 2023;11:1203913. Available from: https://doi.org/10.3389%2Ffpubh.2023.1203913
Kao CY, Zhang YZ, Yang DC, Chen PK, Teng CH, Lin WH, et al. Characterization of host and escherichia coli strains causing recurrent urinary tract infections based on molecular typing. BMC Microbiol [Internet]. 2023;23(1):90. Available from: https://doi.org/10.1186/s12866-023-02820-1
Ahmed AE, Abdelkarim S, Zenida M, Baiti MAH, Alhazmi AAY, Alfaifi BAH, et al. Prevalence and Associated Risk Factors of Urinary Tract Infection among Diabetic Patients: A Cross-Sectional Study. Healthc (Basel, Switzerland) [Internet]. 2023 Mar;11(6). Available from: https://doi.org/10.3390%2Fhealthcare11060861
Simba SM, Omwenga EO, Musyoki SK. Prevalence of E. coli as a causative agent of urinary tract infections and its drug susceptibility patterns among pregnant mothers seeking medicare at Kisii teaching and referral hospital, Kenya. Int J Community Med Public Heal [Internet]. 2022 Feb 28 [cited 2024 Jul 5];9(3):1161. Available from: https://www.ijcmph.com/index.php/ijcmph/article/view/9147
Sangeda R, Paul F, Mtweve D. Prevalence of urinary tract infections and antibiogram of uropathogens isolated from children under five attending Bagamoyo District Hospital in Tanzania: A cross-sectional study. F1000Research [Internet]. 2021;10(449). Available from: https://f1000research.com/articles/10-449/v1
Johnson B, Stephen BM, Joseph N, Asiphas O, Musa K, Taseera K. Prevalence and bacteriology of culture-positive urinary tract infection among pregnant women with suspected urinary tract infection at Mbarara regional referral hospital, South-Western Uganda. BMC Pregnancy Childbirth [Internet]. 2021;21(1):159. Available from: https://doi.org/10.1186/s12884-021-03641-8
Saber S, Yasmin N, Alam MT, Hossain MM, Alam RF. Study on Urinary Tract Infection Among Females of Reproductive Age Group in Tertiary Care Teaching Hospital, Dhaka, Bangladesh. Eur J Med Heal Sci [Internet]. 2021;3(1):85–9. Available from: https://www.ejmed.org/index.php/ejmed/article/download/680/385/2532
Espitia De La Hoz FJ. Urinary Infection in Pregnant Women: Prevalence and Associated Factors in the Eje Cafetero, Colombia, 2018-2019. Urol Colomb [Internet]. 2021;30(2):98–104. Available from: https://www.thieme-connect.com/products/ejournals/pdf/10.1055/s-0040-1722238.pdf
Saquipay Ortega H, Ñauta Uzhca ME, Chacón Jarama V de los Á, Valencia Solorzano MA, Alulema Asqui JO. Prevalencia y factores asociados a infección de vías urinarias en pacientes embarazadas del hospital municipal del Niño y la Mujer de la ciudad de Cuenca de febrero a julio de 2015. Recimundo. 2021;5(3):339–45.
Folliero V, Caputo P, Della Rocca MT, Chianese A, Galdiero M, Iovene MR, et al. Prevalence and Antimicrobial Susceptibility Patterns of Bacterial Pathogens in Urinary Tract Infections in University Hospital of Campania “Luigi Vanvitelli” between 2017 and 2018 [Internet]. Vol. 9, Antibiotics. 2020. Available from: https://doi.org/10.3390/antibiotics9050215
Al-Haifi AY, Al Makdad ASM, Salah MK, Al-Shamahy HA. Urinary Tract Infections in Post Operative Patients: Prevalence Rate, Bacterial Profile, Antibiotic Sensitivity and Specific Risk Factors. Univers J Pharm Res. 2020;5(3):21–6.
Remenik-Zarauz V, Diaz-Velez C, Apolaya-Segura M. Factores asociados a la presencia de patógenos productores de betalactamasas de espectro extendido en infecciones del tracto urinario en una clínica privada de Lima, Perú. Rev Ciencias la Salud [Internet]. 2020 [cited 2024 Jul 5];18(2):1–11. Available from: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S1692-72732020000200029&lng=en&nrm=iso&tlng=en
Zhu C, Liu H, Wang Y, Jiao J, Li Z, Cao J, et al. Prevalence, incidence, and risk factors of urinary tract infection among immobile inpatients in China: a prospective, multi-centre study. J Hosp Infect [Internet]. 2020;104(4):538–44. Available from: https://www.sciencedirect.com/science/article/pii/S0195670119304888
Odoki M, Almustapha Aliero A, Tibyangye J, Nyabayo Maniga J, Wampande E, Drago Kato C, et al. Prevalence of Bacterial Urinary Tract Infections and Associated Factors among Patients Attending Hospitals in Bushenyi District, Uganda. Int J Microbiol [Internet]. 2019 Jan 1;2019(1):4246780. Available from: https://doi.org/10.1155/2019/4246780
Pritam P. Prevalence of urinary tract infections and current scenario of antibiotic susceptibility pattern of bacteria causing UTI [Internet]. Vol. 2, Indian Journal of Microbiology Research. IP Innovative Publication; 2020. p. 7398. Available from: https://www.ijmronline.org/article-details/7398
Sanín-Ramírez D, Calle-Meneses C, Jaramillo-Mesa C, Nieto-Restrepo JA, Marín-Pineda DM, Campo-Campo MN. Etiological prevalence of urinary tract infections in symptomatic pregnant women in a high complexity hospital in Medellín, Colombia, 2013-2015. Rev Colomb Obstet Ginecol [Internet]. 2019 Oct 1 [cited 2024 Jul 5];70(4):243–52. Available from: https://revista.fecolsog.org/index.php/rcog/article/view/3332/3566
Al-Anbari HH, Zghair H, Al-Hilali K. Prevalence of urinary tract infection among university students caused by Escherichia coli and its susceptibility to drug therapy. Eur J Pharm Med Res. 2019;6(8)(8):133–5.
Czajkowski K, Broś-Konopielko M, Teliga-Czajkowska J. Urinary tract infection in women. Prz menopauzalny = Menopause Rev [Internet]. 2021 Apr;20(1):40–7. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077804/
Alghoraibi H, Asidan A, Aljawaied R, Almukhayzim R, Alsaydan A, Alamer E, et al. Recurrent Urinary Tract Infection in Adult Patients, Risk Factors, and Efficacy of Low Dose Prophylactic Antibiotics Therapy. J Epidemiol Glob Health [Internet]. 2023;13(2):200–11. Available from: https://doi.org/10.1007/s44197-023-00105-4
Majrashi AA, Alsultan AS, Balkhi B, Somily AM, Almajid FM. Risk Factor for Urinary Tract Infections Caused by Gram-Negative Escherichia Coli Extended Spectrum ß Lactamase-Producing Bacteria. J Nat Sci Med [Internet]. 2020;3(4). Available from: https://journals.lww.com/jnsm/fulltext/2020/03040/risk_factor_for_urinary_tract_infections_caused_by.6.aspx
Enock K, Nakalema M. Prevalence of urinary tract infection among pregnant women attending antenatal clinic at kasangati health center iv in wakiso district. a descriptive cross-sectional study. Student’s J Heal Res Africa [Internet]. 2023 Jul 7;4(6 SE-):15. Available from: https://sjhresearchafrica.org/index.php/public-html/article/view/451
Dube R, Al-Zuheiri ST, Syed M, Harilal L, Zuhaira DA, Kar SS. Prevalence, Clinico-Bacteriological Profile, and Antibiotic Resistance of Symptomatic Urinary Tract Infections in Pregnant Women [Internet]. Vol. 12, Antibiotics. 2023. Available from: https://doi.org/10.3390/antibiotics12010033
Orellana Ávila MG, Silva Andrade P, Iñiguez Rodriguez D, Mora Verdugo M, Toral Chacón C. Prevalencia de uropatógenos bacterianos y su resistencia antimicrobiana en pacientes con infección al tracto urinario durante el año 2019 en la ciudad de Cuenca. Rev Med Ateneo Junio [Internet]. 2022;24(1):15–29. Available from: http://orcid.org/0000-0003-1198-
Carriel Álvarez M, Ortiz J. Prevalencia de infección del tracto urinario y perfil de susceptibilidad antimicrobiana en Enterobacterias. Rev Vive [Internet]. 2021 May 4 [cited 2024 Jul 5];4(11):217–28. Available from: https://revistavive.org/index.php/revistavive/article/view/103/287
Jaramillo LI, Ordoñez Aristizábal KJ, Jimenez Londoño AC, Uribe Carvajal MC. Perfil clínico y epidemiológico de gestantes con infección del tracto urinario y bacteriuria asintomática que consultan a un hospital de mediana complejidad de Antioquia (Colombia). Arch Med [Internet]. 2020 Jan 3 [cited 2024 Jul 5];21(1):57–66. Available from: https://revistasum.umanizales.edu.co/ojs/index.php/archivosmedicina/article/view/3877/6382
Cobas Planchez L, Navarro Garcia Y, Mezqui de pedro N. Gestantes con infección urinaria pertenecientes a un área de salud del municipio Guanabacoa, La Habana. Rev Médica Electrónica [Internet]. 2016 [cited 2024 Jul 5];43(5):408–11. Available from: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1684-18242021000102748
Barragán Moya GN, Barona Castillo LI, Moreno J, Soliz S, Martínez C. Infecciones del Tracto Urinario: métodos diagnósticos, tratamiento empírico y multirresistencia en una Unidad de Adultos Área de Emergencias. CAMbios HECAM [Internet]. 2020 Dec 29 [cited 2024 Jul 5];19(2):38–43. Available from: https://revistahcam.iess.gob.ec/index.php/cambios/article/view/664/405
Arias Regalado JE, Ochoa Brito M, Enrique Marcano Sanz LE. Prevalencia de infección del tracto urinario y factores asociados en pacientes de 0 a 5 años hospitalizados. Rev Ecuat Pediatr [Internet]. 2021;22(1):1–9. Available from: https://rev-sep.ec/index.php/johs/article/view/98/62
Seid M, Markos M, Aklilu A, Manilal A, Zakir A, Kebede T, et al. Community-Acquired Urinary Tract Infection Among Sexually Active Women: Risk Factors, Bacterial Profile and Their Antimicrobial Susceptibility Patterns, Arba Minch, Southern Ethiopia. Infect Drug Resist [Internet]. 2023 Apr 18 [cited 2024 Jul 5];16:2297–310. Available from: https://www.dovepress.com/community-acquired-urinary-tract-infection-among-sexually-active-women-peer-reviewed-fulltext-article-IDR
Islam MA, Islam MR, Khan R, Amin MB, Rahman M, Hossain MI, et al. Prevalence, etiology and antibiotic resistance patterns of community-acquired urinary tract infections in Dhaka, Bangladesh. PLoS One [Internet]. 2022 Sep 15;17(9):e0274423. Available from: https://doi.org/10.1371/journal.pone.0274423
Mohammed ME, Abdullah EM, Abdullah AM. Prevalence of escherichia coli and its antibiotic susceptibility profiles among patients presenting with signs and symptoms of UTI in Ramadi city. Int J Health Sci (Qassim) [Internet]. 2022 Sep 3;6(S6 SE-Peer Review Articles):9077–87. Available from: https://sciencescholar.us/journal/index.php/ijhs/article/view/12391
Shabani Y, Sadeghi H, Yousefichaijan P, Shabani D, Rafiee F. Prevalence of Risk Factors of Urinary Tract Infections in Infants and Children in Arak, Iran: A Cross-sectional Study. Nephrourol Mon [Internet]. 2023;15(1):e131333. Available from: https://brieflands.com/articles/num-131333
Rasheed HJ, Al-Ruaby KJ, AlQshawi AAH. High Incidence of Escherichia coli – Urinary Tract Infection in Pregnant Women in Iraq. World J Exp Biosci [Internet]. 2022 Oct 19;10(2 SE-Research Article):42–4. Available from: https://wjebio.com/index.php/journal/article/view/150
Zúñiga-Martínez M de L, López-Herrera K, Vértiz-Hernández ÁA, Loyola-Leyva A, Terán-Figueroa Y. Prevalencia de infecciones de vías urinarias en el embarazo y factores asociados en mujeres atendidas en un centro de salud de San Luis Potosí, México. Investig y Cienc la Univ Autónoma Aguascalientes [Internet]. 2019 [cited 2024 Jul 5];(77):47–55. Available from: https://dialnet.unirioja.es/servlet/articulo?codigo=7163185&info=resumen&idioma=SPA
Zubair KU, Shah AH, Fawwad A, Sabir R, Butt A. Frequency of urinary tract infection and antibiotic sensitivity of uropathogens in patients with diabetes: Frequency of urinary tract infection and antibiotic sensitivity. Pakistan J Med Sci [Internet]. 2019 Oct 9;35(6 SE-Original Articles). Available from: https://www.pjms.org.pk/index.php/pjms/article/view/115
Mama M, Manilal A, Gezmu T, Kidanewold A, Gosa F, Gebresilasie A. Prevalence and associated factors of urinary tract infections among diabetic patients in arba minch hospital, Arba Minch province, South Ethiopia. Turkish J Urol [Internet]. 2019;45(1):56–62. Available from: https://urologyresearchandpractice.org/content/files/sayilar/177/buyuk/56-62.pdf
DOI: https://doi.org/10.23857/pc.v9i10.8292
Enlaces de Referencia
- Por el momento, no existen enlaces de referencia
Polo del Conocimiento
Revista Científico-Académica Multidisciplinaria
ISSN: 2550-682X
Casa Editora del Polo
Manta - Ecuador
Dirección: Ciudadela El Palmar, II Etapa, Manta - Manabí - Ecuador.
Código Postal: 130801
Teléfonos: 056051775/0991871420
Email: polodelconocimientorevista@gmail.com / director@polodelconocimiento.com
URL: https://www.polodelconocimiento.com/
